Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Amy: Look, your anxiety levels are right in the zone.
Sheldon: Really? Oh, that's fantastic. No wait, they're dropping. Why are they dropping?
Amy: Because you're happy they're elevated.
Sheldon: Oh, that is infuriating. Oh look, they're going back up again. Terrific. Oh no, they're going back down.

Leonard: At least listen to it through headphones. I'm trying to sleep, good night.
Sheldon: Boy. Taylor was right. Haters gonna hate, hate, hate, hate, hate.

Penny: I love him, but if he's broken, let's not get a new one.

Penny: Shouldn't you be getting ready for work?
Sheldon: I'm not going. Would you like to know why?
Penny: You're sad about not getting any thing done last night, so you're gonna sit around and pout about it.
Sheldon: Boy, I'm not nearly as mysterious as I think I am.

Sheldon: I don't want to tell you how to do your job, but when a mouse completes a maze, it gets a food pellet.
Amy: It also gets its brain plucked out with tweezers.
Sheldon: And its last meal was a food pellet? You're a monster.

Penny: Oh, I'm just doing this awful work out. I hate it.
Sheldon: Well if you hate it, then why are you doing it? Although I could ask the same question about the coitus with Leonard.

Penny: Now you just get comfortable.
Sheldon: No, no. Comfort is the enemy. You know what's comfortable? Slippers, and blankets, and panda bears. Oh, imagine a panda bear with Richard Feynman's face on it!
Warm up the car, Leonard. It's poster time.

Penny: So, whichever rep has the best sales for the quarter gets a trip for two to Hawaii.
Amy: That would be so romantic for you and Leonard.
Penny: Yeah, clearly you haven't seen him on the beach walking around with his metal detector.

Amy: Sheldon, I want you to take that cap off.
Sheldon: That nagging tone is helping my anxiety. But if you could maybe go 10% less shrill, that would really put the zip-a-dee in my doo-dah.

Sheldon: Hey, what are you trying to pull? The President of Science isn't in here.
Leonard: You lie down, he'll be here in a minute.
Sheldon: Okay. I thought you were trying to trick me.

Amy: All canines instinctively know how to swim. Why wouldn't a werewolf have the same abilities?
Bernadette: Well, they're not a hundred percent wolf. They're a werewolf, that's only a part wolf. That's like comparing apples to oranges.
Sheldon: Thank you! Although technically it's apples that turn into were-oranges when the moon is full.

Oh, this is fun. We should do it sometime when you aren't all PMSing.

Sheldon: I knew you'd understand, armadillo Isaac Newton.

Penny: Have fun.
Sheldon: Oh, I will. Nothing more fun than a paradigm shifting evening of science.
Penny: (To Leonard) And you thought it was soaping me up in the shower.

Sheldon: I'm not going to work today. And would you like to know why?
Leonard: You're upset because you spent the whole night working on dark matter and didn't make a break through, and now you're worried you made a huge mistake switching fields, and you're gonna sit around and sulk all day.
Sheldon: Like a big old baby.