Sheldon: And look at the cool incentives I'm offering.
Leonard: "For $50,000, I will examine your diet and create a customized bathroom schedule." That's fitting, 50 grand down the toilet.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Sheldon: So with this level of high-power laser array, we would actually be able to solve the black hole information paradox once and for all.
President Siebert: That's impressive, and how much funding were you looking for?
Sheldon: $20 million.
President Siebert: Really? You think you can build that for $20 million?
Sheldon: Not a chance.
President Siebert: I'm sorry, then why are you asking me for it?
Sheldon: Because once you've spent $20 million, you're much more likely to give me an additional 50.
President Siebert: So actually, what you're saying is with $70 million, you can build this.
Sheldon: I can see why you'd think that, but no. You can't go to the board of trustees and say you gave Sheldon Cooper $70 million and have nothing to show for it. No, the only way you'd be able to save face is to double down.
President Siebert: So 140?
Sheldon: And then double again.
President Siebert: 280?
Sheldon: And then - good news - not quite double again. So, uh, what do you say? We have a deal?

Sheldon: Wow! You look beautiful.
Amy: Really? 'Cause I was gonna return it.
Sheldon: Why would you return it? You look like a pile of swans.

Penny: What if you asked for $20 million?
Sheldon: I'm sorry, I'm trying to do science, not hire Lady Gaga to come to my birthday.
Penny: Do you even know who Lady Gaga is?
Sheldon: Presumably, the wife of Lord Gaga.