Penny: Well, if it makes you feel any better, I'm not feeling so hot either.
Sheldon: Why would that make me feel better?
Penny: I don't know, empathy?

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Raj: Ooo, big talk from a man who was once treed by a chicken.

Sheldon: I am not crazy, my mother had me tested.