Howard: That was weird, right?
Leonard: Was it? I honestly can't tell anymore.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Penny: You know, you compared us to the strangest couple we know, and we know Amy and Sheldon, Howard and Bernadette, Raj and his twitchy little dog.

Amy: How's this for a compromise? Make all the schedules you want, just don't tell me about them.
Sheldon: Excellent. I'll create an algorithm that'll generate a pseudo-random schedule.
Yeah, and do you know why it won't be a true random schedule?
Amy: Because the generation of true random numbers remains an unsolved problem in computer science.
Sheldon: Come with me.
Amy: Where are we going?
Sheldon: To the hotel room. And when we get there, I'm gonna need you to say that again, except naked.

Raj: Sounds like someone's in there.
Bernadette: My God, what if Sheldon and Amy are getting robbed?
Howard: Or worse, what if they're back early?