Howard: How long has he been stuck?
Leonard: Hmm, intellectually about 30 hours, emotionally about 29 years.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Leonard: [to a "smiling" Sheldon] We're here to see Koothrappali, not kill Batman.

Leonard: Penny, I told you if you don't put him in his crate at night, he just runs around the apartment.

Raj: Okay, just to be clear, roller skating was my idea, and I'm very unhappy that you turned it into a double date. I hope you both fall on your asses and break your coccyxes.
Sheldon: The plural of coccyx is coccyges.
Raj: Screw you. Give me back my lima beans.

Penny: What happened?
Leonard: Sheldon's escaped and he's terrorizing the village.