Amy: Oh, that's me. It's CVS. My prescription's ready. [phone vibrates] Oh, and also my dad. He says congratulations and he loves me.
Sheldon: Nothing about me? [phone vibrates] Oh. Oh, it's your dad. I'm good.

Amy: Okay, what is going on?
Penny: We just want you to be prepared for any surprises that could happen tomorrow.
Amy: What surprises?
Bernadette: We don't want to spoil anything, but you should know that Sheldon said he's ready to be physical.
Amy: You shut your damn mouth! You actually heard him say this?
Penny: Yes, he said he wants to do something to show you how much you mean to him.
Amy: I can't believe it. I don't know what to say.
Bernadette: Well, we're really happy for you and we know how much-
Amy: I do know what to say. Let's get me waxed!

Amy: But enough about Penny, let's talk about us. We're looking good.
Bernadette: We are.
Amy: Better than good. I mean look at you, your body's bangin'.
Bernadette: Amy!
Amy: Don't Amy me. We're always talking about how hot Penny is. Come on, scientist to scientist, how big are those hadron colliders?

Amy: Do you have any idea how hard it is to laugh at a knock knock joke that starts "Knock Knock Knock, Amy. Knock Knock Knock, Amy. Knock Knock Knock, Amy"?

Amy: Oh. That's me. Hello? Yes, this is Dr. Fowler. I see. Okay, thank you. We won.
Penny: Congratulations!
Leonard: Oh, my God!
Sheldon: We did it.
Amy: I know. Can you believe it?
Sheldon: That's a good point. What if I'm dreaming? [Leonard slaps Sheldon] We won the Nobel Prize!

Sheldon: It's happening! [phone chimes] Unknown caller. It's got to be them.
Amy: Okay, put it on speaker.
Sheldon: Hello?
Amy: Hi.
Barry Kripke: Hello. This is Sweden calling. Is this Dr. Cooper and Dr. Fowler?
Sheldon: Yes.
Amy: Yeah.
Barry Kripke: Congratulations. It is my pleasure to inform you that you've won the Nobel Prize in being suckers!

Penny: So, I guess the only thing that actually stays the same is that things are always changing.
Sheldon: Interesting. So you're saying the inevitability of change might be a universal constant.
Penny: Well, there's a little more to it than that, but, yeah, sure.