Amy: If Sheldon proposed to me during sex, my ovaries would grab onto him and never let go.

Amy: Okay, what is going on?
Penny: We just want you to be prepared for any surprises that could happen tomorrow.
Amy: What surprises?
Bernadette: We don't want to spoil anything, but you should know that Sheldon said he's ready to be physical.
Amy: You shut your damn mouth! You actually heard him say this?
Penny: Yes, he said he wants to do something to show you how much you mean to him.
Amy: I can't believe it. I don't know what to say.
Bernadette: Well, we're really happy for you and we know how much-
Amy: I do know what to say. Let's get me waxed!

Sheldon: Sheldon Cooper does not get lucky.
Amy: You and me both, brother.

Amy: Do you have any idea how hard it is to laugh at a knock knock joke that starts "Knock Knock Knock, Amy. Knock Knock Knock, Amy. Knock Knock Knock, Amy"?

Mrs. Wolowitz I'm not going near that fakakta thing. I'll catch a computer virus.
Howard: You can't catch a computer virus.
Mrs. Wolowitz Oh, so now you're an astronaut and a doctor?

Sheldon: Amy, when I look in your eyes and you're looking back in mine, everything feels not quite normal. Because I feel stronger and weaker at the same time. I feel excited and, at the same time, terrified. The truth is, I don't know what I feel, except I know what kind of man I want to be.
Amy: Sheldon, that was beautiful.
Sheldon: I should hope so, that's from the first Spider-Man movie.
Amy: I'll take it.

Mrs. Wolowitz: Wives don't take boys from their mothers.