Leslie: Boy, your heart's racing. I must've really gotten you going.
Wolowitz: Well, it's partly you, partly my transient idiopathic arrhythmia.
Leslie: Sexy.

Leslie: There's no reason to feel uncomfortable just because we've seen each other's faces and naked bodies contorted in the sweet agony of coitus. Rest assured that any aspects of our sexual relationship regarding your preferences, your idiosyncrasies, your performance, are still protected by the inherent confidentiality of the bedroom.

Leslie: Hello men. Sheldon.

Leslie Winkle: Uh, in the past, I would've said something obnoxious, like, "Happy birthday, dumbass". But I'm not gonna do it. You and I have both grown a lot, and it's just so nice to see you all again. So happy birthday, Sheldon.
Sheldon: Oh. Oh, now, you know I hate change. Say it.
Leslie Winkle: Happy birthday, dumbass!

Howard: [looking at his caller ID] Ooh, looks like I'm gonna have sex tonight. [answering phone] Hey, baby...
Penny: His right hand is calling him?

Penny: What are we gonna do?
Leonard: We? No, no, no. You had your chance to be "we" for like a year and a half now. Right now, you are you and you are screwed!

Raj: We need a plan. How about Operation Hammer of the Gods?
Leonard: I forget, which one is Hammer of the Gods?
Raj: We hide behind the dumpsters in the parking lot and ambush people when they come to pee.