Sheldon: I believe in a gender blind society like in Star Trek. Where women and men of all races and creeds worked side-by-side as equals.
Leonard: You mean where they were advanced enough to develop an interstellar warp drive, but a black lady still answered the space phone?

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Bernadette: We can't all be Cinderella.
Amy: Then how do we decide?
Bernadette: Well, it's simple. This was my idea. I'm driving. I'm Cinderella. You bitches got a problem with that, we could stop the car right now.

Sheldon: (Typing into a search engine) How do I get 12-year-old schoolgirls excited?
Howard and Leonard: No!

Bernadette: Every one of you has the capacity to be anything you want to be.
Penny: Unless you want to be Cinderella.
Bernadette: Come at me. See what happens!