Sheldon: Oh, I'm fine. It's just some stomach medication for my trip. There's a remote yet distinct possibility that I may end up in South America.
Penny: Remember the old days when I would have said something dumb like "Why?"

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Bernadette: Raj, your tag's sticking out. *Bernadette tucks Raj's clothing tag back in*
Raj: Thank you. That's the closest I've come to sex in like two years.
Bernadette: Now I feel a little gross.
Raj: You're only making it seem more real for me.

Sheldon: I have one question. Is this a prank? Where you land in Houston and you've made up wanted posters which have my face with a moustache and a Spanish name, and I get arrested and deported to South America?
Howard: No.
Sheldon: Well I'm glad, because I would not have seen that coming.

Howard: Listen, I was thinking you and I could probably try to be better friends.
Sheldon: Really? I was thinking what we have now is a bit much.