Leonard: Homo habilis discovering his opposable thumbs says what?
Kurt: What?

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Leonard: I call Frodo!
Sheldon, Raj, and Howard: Damn!

Leonard: We all have other costumes, we can change.
Raj: Or we could walk right behind each other all night. It'll look like one person going really fast.

Sheldon: Given the reaction to my costume, this party is a scathing indictment of the American educational system.
Kurt: You're a zebra, right?
Sheldon: (to Leonard) Yet another child left behind.