Penny: [on the phone] No, mom. It's the same guy I've been going out with for the past two years. Yeah, the scientist. Well, it's complicated. He works with lasers and atomic magnets. No, I did not see it coming. No, we have not set a date. No, I am not pregnant. Yeah, this is a first for our family.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: Hang on, I know a place where you could you stay and earn some money at the same time.
Stuart: Great!
Howard: I just have to warn you: it will involve humiliation, degradation and verbal abuse.
Stuart: So, what's the catch?

Bernadette: But we have jobs, we can't babysit her twenty-four hours a day.
Howard: What if we use our vacation time?
Bernadette: I wanted to go to Hawaii, not Hell.

Sheldon: I'm writing an appeal to the faculty senate so that I can move on from string theory.
Leonard: How's it going?
Sheldon: You tell me. "Dear esteemed colleagues. As you may know, I have requested to change my field of study. My decision to do so is, I believe, in the best interest of science. At your convenience, I'd be happy to explain it to you in words you'll understand."