Bernadette: Guess who won a hundred dollars playing craps?
Penny: That's a dollar.
Bernadette: Guess who wildly over-tipped a cocktail waitress?

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Sheldon: I know the real reason you never made progress with that idea. You thought of it September 22nd, 2007. Two days later, Penny moved in and so much blood rushed to your genitals, your brain became a ghost town.

Amy: But enough about Penny, let's talk about us. We're looking good.
Bernadette: We are.
Amy: Better than good. I mean look at you, your body's bangin'.
Bernadette: Amy!
Amy: Don't Amy me. We're always talking about how hot Penny is. Come on, scientist to scientist, how big are those hadron colliders?

Leonard: Penny is not the reason I did not pursue that idea.
Sheldon: Oh really? Since meeting her, what have been your greatest accomplishments?
Raj: Easy. Sleeping with Penny.
Howard: Getting Penny to go back out with him after she dumped him.
Raj: Tricking Penny into getting engaged.
Howard: And a few weeks ago he almost did a pull-up!