Howard: I'm telling you, something is wrong. I can always feel it when Raj is in trouble.
Bernadette: Geez, how close were you guys before we got married?
Leonard: Don't look under that rock.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Sheldon: She's remarkable.
Leonard: She really is.
Sheldon: How is it that she can remember all those lines, yet as a waitress she can't remember no tomato on my hamburger?

Bernadette: It smells pretty ripe in here. You kinda feel it in your eyes.

Lucy: I'm kind of broken.
Raj: That's great. I'm broken, too.
Lucy: Oh, no you're not.
Raj: Oh, I totally am. If it wasn't for this beer, I couldn't even talk to you right now. I'm a wreck. There are many things seriously wrong with me. And not quirks, either. Like diagnosable psychological problems. Maybe brain damage.
Lucy: Well how do I know you're not just saying that?
Raj: Go out with me on one date. I promise you, you'll see.