Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Raj: Can we take a moment to discuss that I just lied to the government for you?
Howard: Yeah, I would not have done that for you.

Sheldon: Do you think your father's doing unspeakable things to my mother?
Leonard: No.
Sheldon: Are you saying that because the things are unspeakable?
Penny: Your parents are old. Anything unspeakable was finished by 9:30.

Bernadette: Love is patient, but it's not gonna put up with all the side chatter, so let's knock it off!
Howard: At least she's yelling at someone else for a change.
Bernadette: Howard!

Penny: Okay, I understand everyone's a little tense today, so I am just gonna get to the important stuff. Leonard, standing here with you in front of our family and friends is bringing up a lot of feelings. Like what a good idea it was to elope the first time. But also how incredibly happy you make me. Thank you for marrying me. Hopefully for the last time.

Sheldon: Why do people cry at weddings?
Mary Cooper: They're practicing for what's coming later.

Beverly Hofstadter: I don't see why I should have to watch your father parade around with some Bible-thumping bumpkin.
Sheldon: Oh. Excuse me, that is my mother you're talking about, however accurately.

Raj: What's the worst that could come of this meeting?
Howard: I don't know. They take the invention away, and I get nothing?
Raj: Okay, that's not so bad. You know what happened to the scientists that worked on the Manhattan Project? The government forced them to move to the desert. They had to live in secret, and when Oppenheimer objected to what they made him do, they destroyed his reputation.
Howard: What's the point of that story?
Raj: I just read a book about Oppenheimer, seemed like a chance to show off.

Amy: Sheldon, your mother's an attractive woman. You need to get used to the fact that men are going to be interest in her.
Sheldon: Well, and you need to drive the car and mind your business.
Amy: I will not have you be disrespectful to me.
Sheldon: What- you're not my mother.
Mary Cooper: Don't you be disrespectful to her.
Sheldon: Yes ma'am.
Mary Cooper: You'll get there. You've just gotta put some zing on it.

Bernadette: I now pronounce you husband and wife. And weird other husband who came with the apartment.

Susan: Penny, I don't know what I was worried about. Your friends are just lovely.
Penny: Oh, thanks, Mom.
Susan: Although that Sheldon is a bit peculiar.
Penny: Is he? I never noticed.
Wyatt: He reminds me of that turkey we had who drowned looking up at the rain.

Sheldon: Did that conversation include the phrase "your genitals are a joy to behold"?
Alfred Hofstadter: Look, I promise you, neither I, nor anyone, has ever said that.
Leonard: You don't know his girlfriend very well.
Sheldon: Or what a joy it is to behold my genitals.

Raj: It is funny when you think about it.
Howard: Maybe to you. You didn't get a $500 traffic ticket.
Bernadette: Because you were driving like a lunatic.
Howard: Hey, if thinking secret government agents are chasing you makes you a lunatic, then yeah, okay.

Susan: All right, that's enough jail talk.
Randall: Penny knows where I was; she sent me cigarettes.
Susan: You sent your brother cigarettes?
Wyatt: He was cooking and selling crystal meth, Susan. I think we can let the cigarettes slide.

Randall: You know, It's hard to believe I've never met Leonard.
Wyatt: Well, he probably buys his illegal drugs from a local vendor.
Susan: Not funny, Wyatt.
Penny: I thought it was really funny.
Wyatt: Thanks.