Wyatt: Welcome to the family, Leonard. Don't lend your new brother-in-law money.

Wyatt: I want grandkids before I die and I want 'em to grow up in a house without wheels.

Susan: Penny, I don't know what I was worried about. Your friends are just lovely.
Penny: Oh, thanks, Mom.
Susan: Although that Sheldon is a bit peculiar.
Penny: Is he? I never noticed.
Wyatt: He reminds me of that turkey we had who drowned looking up at the rain.

Susan: All right, that's enough jail talk.
Randall: Penny knows where I was; she sent me cigarettes.
Susan: You sent your brother cigarettes?
Wyatt: He was cooking and selling crystal meth, Susan. I think we can let the cigarettes slide.

Raj: Can we take a moment to discuss that I just lied to the government for you?
Howard: Yeah, I would not have done that for you.

Sheldon: Do you think your father's doing unspeakable things to my mother?
Leonard: No.
Sheldon: Are you saying that because the things are unspeakable?
Penny: Your parents are old. Anything unspeakable was finished by 9:30.

Bernadette: Love is patient, but it's not gonna put up with all the side chatter, so let's knock it off!
Howard: At least she's yelling at someone else for a change.
Bernadette: Howard!