Sheldon: I need access to the Cheesecake Factory's walk-in freezer.
Penny: Now, honey, I already told you, the hamburger meat is fresh and stored at a safe temperature.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Raj: Well, I'm a Hindu. My religion teaches that if we suffer in this life we are rewarded in the next. Three months at the North Pole with Sheldon and I'm reborn as a well-hung billionaire with wings.

Leonard: Howard, this is big science. You could be the engineer who builds the equipment that puts us on the cover of magazines.
Howard: I could also be the engineer who builds the crossbow that kills Sheldon.

Sheldon: Leonard, you may be right. It appears that Penny secretly wants you in her life in a very intimate and carnal fashion.
Leonard: You really think so?
Sheldon: Of course not. Even in my sleep-deprived state, I've managed to pull off another one of my classic pranks. Bazinga!