Leonard: Howard, this is big science. You could be the engineer who builds the equipment that puts us on the cover of magazines.
Howard: I could also be the engineer who builds the crossbow that kills Sheldon.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Bernadette: Maybe we should get one of those machines to help her up the stairs.
Howard: You mean a forklift?

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Raj: Well, I'm a Hindu. My religion teaches that if we suffer in this life we are rewarded in the next. Three months at the North Pole with Sheldon and I'm reborn as a well-hung billionaire with wings.

Sheldon: Leonard, you may be right. It appears that Penny secretly wants you in her life in a very intimate and carnal fashion.
Leonard: You really think so?
Sheldon: Of course not. Even in my sleep-deprived state, I've managed to pull off another one of my classic pranks. Bazinga!

Mrs. Koothrappali: I told you no. Why don't you believe me?
Mrs. Wolowitz Cause it doesn't make sense to me. How can it be that in the entire country of India, there isn't one Outback Steakhouse?