Leonard: No offense, but shower sex with you is now the second best thing that's happened today.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Sheldon: Ah, memory impairment; the free prize at the bottom of every vodka bottle.

Sheldon: Are you suggesting I play dirty?
Amy: Yes, dirty. Dirty, dirty, dirty. Which brings me to our next order of business. [kisses Sheldon]
Sheldon: Fascinating.
Amy: I hope you don't take what I'm about to do as a comment on what we just did. [runs to bathroom and vomits]

Sheldon: The mean Indian lady tried to make me eat lamb.