Penny: Dr. Sheldon Cooper?
Ramona: We're having dinner.
Penny: Sheldon Cooper? Tall, thin, looks a little like a giant praying mantis.
Ramona: He is cute, isn't he?

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Raj: Isn't there a policy against dating graduate students?
Leonard: No, if you can talk to them, you can ask them out.
Raj: Damn, there's always a catch.

Penny: Whats Sheldon's deal? Is it girls, guys, sock puppets?
Howard: We operate on the assumption that Sheldon has no deal. Though we have many theories about how he might reproduce. I'm an advocate of mitosis.
Penny: What?
Howard: I believe that one day Sheldon will eat an enormous amount of Thai food and spilt into two Sheldons.

Penny: Holy crap on a cracker!