Penny: Bernadette, for every episode of Doctor Who Leonard has made me sit through, I will play on your behalf and send that TARDIS back to Gallifrey, where I hate that I know it belongs.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Amy: Have you made a decision about the TARDIS? I think I can sell it if we call it Big British Portapotty.

Sheldon: Amy, the Daleks are right on my tail. Quick, we need to reset the time circuits. Oh no, I left my Sonic Screwdriver behind.
Amy: Really should have thought this through.

Howard: Come on, one day this may double in value and be worth half what I paid for it!