Bernadette: If you're really worried, we'll take him to the vet and have him tested. Good.
Howard: Thank you. Oh, okay, there is a test! All they have to do is ... cut off his head and check his brain.
Bernadette: Oh, cut off his head? That's where his little nose is.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Sheldon: Oh, and speaking of Valentine's Day, I haven't forgotten about you tonight.
Amy: What do you mean?
Sheldon: Well, you've become such an integral part of my life as well as this show, I felt it only right to include your name in the title.
Amy: Oh, that is so sweet.
Sheldon: So from now on, this program will be officially known as Dr. Sheldon Cooper and Dr. Amy Farrah Fowler present Dr. Sheldon Cooper's Fun With Flags.
Amy: Catchy.

Amy: Since we're live, you'll finally be able to reach out to us with your flag thoughts and flag questions.
Sheldon: Allow us to answer a few quick ones that we get all the time. Uh, yes, I really am a doctor. Uh, yes, she really is my girlfriend.
Amy: No, I just blink a lot, it's not Morse code for "rescue me."

Raj: But, Amy, when you and Sheldon split up, didn't you start dating someone right away? Amy: Well, I ... I wouldn't say right away.
Sheldon: And actually, it was three different men.
Barry Kripke: Three different men?! Damn, girl, way to give the milk away!