Sheldon: What self-important preening fraud are they honoring this year?
Leonard: I'm so glad you asked it like that. You!

Sheldon: I remember the song! It's called "Darlin'" by the Beach Boys! Oh, thank goodness! I'm not crazy! I don't have to take a pigeon as my bride!
Leonard: There goes our shot at him living on the roof.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Penny: So what do you say Sheldon, are we your X-men?
Sheldon: No, the X-men were named for the X in Charles Xavier. Since I am Sheldon Cooper, you will be my C-men.

Sheldon: I see. I assume since the rest of you have set the bar so low, you're saving the most impressive contribution for last. Go on Howard, dazzle me.
Howard: Well, my power is the ability to pretend like I give a damn about your piddly-ass problem. And that's 24/7 buddy.

Sheldon: A neutron walks into a bar and asks how much for a drink. The bartender replies "for you, no charge".