Howard: Ma, Ma, calm down. Listen to me. I know it says click with the mouse, but on a laptop, the trackpad is the mouse. Now, put your finger on it. Doesn't matter which finger. Good choice. Now move it down to your e-mail icon. Yeah, the little envelope. What do you mean, what does it look like? It looks like an envelope! Fine, you don't like the computer, don't use it! Sure, we can exchange it for a salad spinner. Goodbye!

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Bernadette: Maybe we should get one of those machines to help her up the stairs.
Howard: You mean a forklift?

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Sheldon: I'm not saying that all senior citizens that can't master technology should be publicly flogged. But, if we made an example of one or two it might give the others incentive to try harder.

Raj: Ooh, Leonard is going all alpha nerd on Sheldon's ass.

Leonard: I had a great idea. Do you know how we're always having to stop and solve differential equations, like when you're doing Fourier equations or using the Schroedinger equation?
Sheldon: Howard doesn't, he's only an engineer.