Bernadette: Things going well with you and Sheldon living together?
Amy: Better than ever. He asks about my day, takes an interest in my life. He's like my boyfriend in college, except he's real, so people can see him.
Bernadette: I've been seeing him for years. I'm still not convinced he's real.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Leonard: I would pull this car over and kick you out, but if Penny dumps me, you're all I got.

Sheldon: Amy is free. She had a harp lesson on Saturday, but it got canceled. Boy, when you take an interest in people, you really uncork a geyser of nonsense.

Raj: No offense to her father, but he's not an MIT-trained engineer. Thinking and building is what you do.
Howard: MIT's motto is "Mind and Hand," which just so happens was also my motto as a lonely teenager.