Penny: Amy, what's wrong?
Amy: My boyfriend's a jerk.
Penny: Well, I know he didn't cheat on you, so what happened?

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Raj: But excuse me, I have something to say. None of you may realize it, but I was very much looking forward to this weekend. It was gonna be like the old days -- the four of us hanging out, playing video games, before you guys all got girlfriends. Do you have any idea what it's like to be the only one without a girlfriend? Even if I get one someday, I'll still be the guy who got a girl after Sheldon Cooper!

Leonard: We'll miss you Sheldon.
Sheldon: Yeah, well, who wants to spend the whole weekend, running around a bunch of pretend planets, battling made up monsters? That's for babies.
Howard: Yeah, but it's got lightsabers.
Sheldon: Please, Amy! It's got lightsabers!

Howard: Look, if you don't want to go to the party, just don't go. You're a grown man. Act like one. Tell Amy you want to spend the weekend having a sleepover and playing video games with your friends!