Howard: Look, if you don't want to go to the party, just don't go. You're a grown man. Act like one. Tell Amy you want to spend the weekend having a sleepover and playing video games with your friends!

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Josh: So, I have to ask, was the robot sexy?
Howard: It was actually just a mechanical hand.
Josh: 'Cause that's all you need, right?
Howard: You are my brother.

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Raj: But excuse me, I have something to say. None of you may realize it, but I was very much looking forward to this weekend. It was gonna be like the old days -- the four of us hanging out, playing video games, before you guys all got girlfriends. Do you have any idea what it's like to be the only one without a girlfriend? Even if I get one someday, I'll still be the guy who got a girl after Sheldon Cooper!

Leonard: We'll miss you Sheldon.
Sheldon: Yeah, well, who wants to spend the whole weekend, running around a bunch of pretend planets, battling made up monsters? That's for babies.
Howard: Yeah, but it's got lightsabers.
Sheldon: Please, Amy! It's got lightsabers!

Leonard: I'd make fun of Sheldon for having girl problems, if I wasn't shocked that Sheldon has girl problems.