Wil: Hey, I'm having a party at my house on Friday, and I was hoping you would stop by.
Stuart: Will there be girls there?
Wil: Yeah, of course.
Stuart: 'cause there wasn't last time.
Wil: There will be girls.

Wil Wheaton: Game over, Moonpie.

Wil Wheaton: Did that guy just say "Revenge is a dish best served cold" to me in Klingon?

Wil Wheaton: Hey look, they named their team after me!

Penny: Wait, what is going on?
Sheldon: In case you have forgotten, Schrodinger's cat is a thought experiment.
Penny: No, no, no, no, I didn't forget. Um, there's this cat in a box and until you open it, it's either dead or alive or both. Although, back in Nebraska, our cat got stuck in my brother's camp trunk, and we did not need to open it to know there was all kinds of dead cat in there.
Amy: Homespun stories, knowledge of physics and a bosom that defies it. You're the whole package, aren't you?

Amy: It's not for us to judge. We're just here to provide comfort and support while you come to grips with what a despicable thing you've done.

Amy: Now Sheldon, I know you're a left handed monkey wrench but you seriously have a mortal enemy
Sheldon: Yes, in fact I have 61. Would you like to see the list?