Amy: Well, as much as we've studied the brain, there's still a lot we don't know about dreams and their function. You know, even psychologists are divided on it.
Leonard: Mm, it's true. Freud thought dreams were about sex, Adler thought they were about dominance-
Penny: Then again, mine are just about being married to this little guy.
Leonard: Well, now it's just edging into mockery.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Bernadette: One of the great things about being pregnant is drinking cranberry juice out of a wineglass and watching people freak out.

Sheldon: I call this meeting of the Council of Sheldons to order. Let's take roll. Science Sheldon?
Science Sheldon: Present.
Sheldon: Texas Sheldon?
Texas Sheldon: Howdy.
Sheldon: Fanboy Sheldon?
Fanboy Sheldon: Greetings.
Sheldon: Germaphobe Sheldon?
Germaphobe Sheldon: Say it, don't spray it.
Humorous Sheldon: Where's Jock Sheldon?
Sheldon: Not the time, Humorous Sheldon!

Sheldon: Why can't there just be one week each month for famous people to die?
Amy: Well, they've already arranged to die in threes. What more do you want from them?