Amy: Thank you, your majesties. Thank you to the Nobel Committee. We are deeply honored. I would just like to take this moment to say to all the young girls out there who dream about science as a profession: go for it. It is the greatest job in the world. And if anybody tells you you can't, don't listen. And now, speaking of not listening, my husband, Dr. Sheldon Cooper.

Raj: Just remember, you're in charge. Don't let her pull you.
Bert: That seems like an unnecessary thing to say.

Leonard: Are you kidding me? You just found out that a woman who has loved and cared for you for 12 years is pregnant, and all you can say is you're relieved that she's not gonna get you sick?
Sheldon: There's no need for a recap. I was there.

Amy: Why didn't you tell me?
Penny: I didn't tell anybody.
Amy: I'm not anybody. I'm your best friend.
Bernadette: What's going on?
Amy: She's pregnant.
Bernadette: That's fantastic! Why didn't you tell me?
Amy: She didn't tell me, either.
Bernadette: But I'm her best friend.
Amy: [chuckles] We'll get into that later.

Leonard: What kind of DNA is this, anyway?
Sheldon: I was trying to design the genetic code of an advanced race of human being. One of my rare failures, actually.
Leonard: What went wrong?
Sheldon: The balls kept sticking to my pants.

Bernadette: Now, Michael, Mommy and Daddy are going away for a couple days, so if you're gonna say your first words, you got to do it now or wait till we get back.

Sheldon: "Your majesties, members of the Nobel Academy. When I was a young boy growing up in East Texas I always knew I'd wind up on this stage, and everybody who said I wouldn't looks pretty darn foolish right now. I'm talking about you, high school science teacher Mr. Hubert Givens."
Amy: Sheldon, Sheldon. Why are you talking so fast?
Sheldon: I'm trying to get my speech down to 90 minutes.
Amy: Nobody's gonna be able to understand a word you're saying.
Sheldon: Welcome to my life.

Amy: Sheldon, this isn't about ruing. This is about humbly accepting a great honor.
Sheldon: Amy, we won the Nobel Prize in Physics. Humility is for people who win the goofy Nobels like Literature, Economics and Peace.
Amy: Please tell me that's not in your speech.
Sheldon: Oh. I can cut it, but it's the only joke I have.

Sheldon: All right, bagels down. Before we head to the airport, I'd like to go over a few things.
[others groan]
Sheldon: From the moment we step off the plane, each and every one of you is an ambassador for Amy and myself.
Howard: [to Bernadette] I told you these tickets weren't free.

Sheldon: "Number one, in Sweden, punctuality is taken very seriously. In other words, the loosey-goosey attitude in Helsinki will not fly in Stockholm."
Amy: "Two, at the beginning and end of all business and social meetings, shake hands with everyone present: men, women and children."
Sheldon: Yes, you're all encouraged to pair off and practice this once we're in the air and the seat belt sign is off.

Sheldon: All right, well, we should head out now if we're gonna get to the airport six hours before boarding.

Sheldon: Well done. You know, you're proving to be an invaluable part of my entourage.
Leonard: Cool.

Bernadette: Hi, Stuart, just checking in. Seeing if everything's okay.
Stuart: Oh, yeah, we're having fun. Me, Halley and Denise played hide-and-seek all day.
Howard: Oh, that's nice.
Stuart: Yeah. I found Denise right away.
Bernadette: Where was Halley hiding?
Stuart: Uh, the important thing is she's not there now.

Bernadette: Okay, so, everyone's happy and healthy?
Stuart: Well, that depends.
Bernadette: What's that mean?
Stuart: Uh, how many teeth did Halley have when you left?
Howard: All of them.
Stuart: Oh, yeah, that's-that's what I was afraid of.
Bernadette: What happened?
Stuart: Um, well, all right. Um, Michael had a little fever last night.
Bernadette: Michael had a fever?
Stuart: Do you want to hear about Halley or not?
Howard: What happened, Stuart?
Stuart: He was running a little fever, nothing to worry about. And Halley, bless her heart, wanted to bring him his boo-boo bear, so she climbed over the safety rail and took a little tumble down the stairs.
Bernadette: She fell down the stairs?!
Stuart: [stammers] She rolled down the stairs, laughing the whole time. [chuckles] Anyway, when she got to the bottom, there was a tooth missing.
Bernadette: Oh, Stuart!
Stuart: She's fine! She thought it was funny.
Howard: Did you at least save it for the tooth fairy?
Stuart: No, we couldn't find it. We have a theory about where it is, but it'll take six to eight hours to confirm. Speaking of which, where do you keep the spaghetti strainer?

Penny: Leonard, I can't go home. I have to be there for Amy.
Leonard: Yeah. I was thinking that, too. As angry as I am at Sheldon, I still want to see him win that medal.
Penny: It's so strange. No matter how thoughtless and selfish he is, I still love him.
Leonard: If you think about it, he has kind of been our practice kid.
Penny: Like when you make pancakes and the first one comes out a little wonky?
Leonard: The university prefers "quirky."