Howard: Sheldon, don't take this the wrong way, but, you're insane.
Leonard: That may well be, but the fact is it wouldn't kill us to meet some new people.
Sheldon: For the record, it could kill us to meet new people. They could be murderers or the carriers of unusual pathogens. And I'm not insane, my mother had me tested.

Leonard: [to a "smiling" Sheldon] We're here to see Koothrappali, not kill Batman.

(Sheldon smiles in a grotesque way).
Howard: Oh crap that's terrifying.

Sheldon: I often forget other people have limitations. It's so sad.
Howard: He can feel sadness?
Leonard: Not really. It's what you and I would call condescension.

Sheldon: In Papua New Guinea, there's a tribe when a hunter flaunts his success to the rest of the village, they kill him and drive away evil spirits with a drum made of his skin. Superstitious nonsense, of course, but one can see their point.

Raj: Hey, buddy, I'm gonna be in People Magazine.
Charlie Sheen: Yeah, call me when you're on the cover.

Raj: Dr. Gablehouser.
Dr. Gablehouser: Dr. Koothrapali.
Leonard: Dr. Gablehouser.
Dr. Gablehouser: Dr. Hofstadter.
Sheldon: Dr. Gablehouser.
Dr. Gablehouser: Dr. Cooper.
Howard: Dr. Gablehouser.
Dr. Gablehouser: Mr. Wolowitz

Sheldon: You know, this situation with Koothrappali brings to mind a story from my childhood.
Howard: Oh, goody, more tales from the Panhandle.
Sheldon: That's Northwest Texas. I'm from East Texas, the Gulf region. Home to many Vietnamese shrimpers.
Leonard: Do the shrimpers feature in your story?
Sheldon: No. Anyway, when I was eight, a Montgomery Ward delivery van ran over our family cat, Lucky.
Howard: Lucky?
Sheldon: Yes, Lucky.
Leonard: He's irony-impaired. Just move on.
Howard: Ok, dead cat named Lucky. Continue.

Raj: Welcome to the Raj Majal.

Raj: It's not part of my heart-warming and personal narrative, in which a humble boy from New Delhi overcame poverty and prejudice and journeyed to America to reach for the stars.
Howard: Poverty? Your father's a gynaecologist. He drives a Bentley.
Raj: It's a lease.

Sheldon: How will Raj ever reach true greatness if his friends lower the bar for him? When I was eleven, my sister bought our father a "world's greatest dad" coffee mug, and frankly the man coasted until the day he died.

Raj: They're going to digitally add a supernova they say its the perfect metaphor for my incandescent talent.
Sheldon: Yes, a giant ball of gas that collapses on itself.

Sheldon: Hey! Look I found my missing neutrino.
Howard: Oh, great! We can take it off the milk carton.

Raj: So, Saturday night. Can I count on my posse?
Howard: Jeez, I'd love to Raj but I can't make it.
Raj: Ah, okay, Leonard?
Leonard: Oh, ah, oh, I can ... no.
Raj: Sheldon?
Sheldon: I can make it but I won't.

Raj: Boy, I bet Ellen Page's friends aren't giving her this kind of crap!