Sheldon: You're holding a Japanese puzzle box, which takes ten precise moves to open. First, locate the panel with the diamond pattern and slide the centre portion one millimetre to the left. Then, on the opposite end of the box, slide the entire panel down two millimetres. You'll hear a slight click.
Penny: Hang on. Sheldon, do you have any emotional attachment to this box?
Sheldon: No, it's a novelty I ordered off the Internet. Now, did you hear the click?
Penny: Not yet. (Puts the box on the ground and stomps on it)There it is.

Sheldon: So, I'm thinking, you won the Nobel Prize what, three years ago? So you must deal with a whole lot of what has Smoot done lately? My thought is we continue my research as a team, you know, Cooper-Smoot, alphabetical, and when we win the Nobel Prize, you'll be back on top.
George Smoot: With all due respect, Dr. Cooper, are you on crack?
Sheldon: Fine! Smoot-Cooper. Wow, what a diva.

Sheldon: Leonard, let me tell you something. Personal robots cannot get here soon enough.

Raj: It's hot in here. It must be Summer.
Summer Glau: That's cute.
Raj: Really? I just made it up. Have you seen Slumdog Millionaire?
Summer Glau: Oh, yeah, I loved it.
Raj: It's loosely based on my life.