Leonard: How you feeling about it?
Raj: Uh, to be honest, I'm pretty anxious. I mean, this is the woman I'm marrying. What if it's no good? Do we break up? Do we sign on for a lifetime of mediocre sex?
Leonard: Just don't put so much pressure on it. It's always a little awkward in the beginning. I remember the first time I slept with Penny.
Raj: It was bad?
Leonard: Oh, it was awesome! I will replay it in my head until the day I die.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Sheldon: So the doctor prescribed Nizoral and it blocked enzyme action, and the fungus cleared right up.
Mrs. Fowler: That's a very disturbing picture.
Sheldon: Yes, well, they say a picture's worth a thousand words, but I say nothing beats a picture and a thousand words.
Mrs. Fowler: Still, you might want to take it off Facebook.
Sheldon: Oh, no. It's in my nature to share.

Mrs. Fowler: I don't know about you, but I don't really like magic.
Sheldon: You just keep getting better and better.

Howard: Hey, have you checked the dates on these? They're all expired.
Stuart: You buy candy in a comic book store, you get what you get.