Leonard: Just seems dumb to not use the laser.
Stuart: Not as dumb as unleashing a plague on mankind, but, hey, what do we know?
Leonard: Literally nothing.

Stuart: Oh, Sheldon, I'm afraid you couldn't be more wrong.
Sheldon: More wrong? Wrong is an absolute state and not subject to gradation.
Stuart: Of course it is. It's a little wrong to say a tomato is a vegetable, it's very wrong to say it's a suspension bridge.

Stuart: Would you mind stocking these?
Denise: Actually, I'm not on the clock today. I'm just hanging out with my boyfriend.
Stuart: Ah, cool. Huh. That's me, right?
Denise: Oh, I forgot to tell you, I broke up with you, and now I'm dating that guy.
Stuart: I know you're joking, but my flight-or-flight response doesn't.
Denise: Isn't it fight-or-flight?
Stuart: Not for me.

Stuart: Whoa, whoa. You're not gonna cut open a meteor, are you? Have you not learned anything from comic books? Space viruses? Pod people? I sell nothing but warnings.

Stuart: Whoa, whoa. You're not gonna cut open a meteor, are you? Have you not learned anything from comic books? Space viruses? Pod people? I sell nothing but warnings.

Howard: And then Andy said if we want privacy, we should plant some trees. The only way I know how to do that is to give a dollar and tree shows up in Israel.

Denise: If you want cold medicine, Stuart has the entire run of DayQuils, including the rare "DayQuilt" misprint from 1996.
Stuart: What can I say? I'm a collector.