Wil Wheaton: Hello.
Howard: [imitating Shatner] Wil, Bill Shatner here.
Wil Wheaton: Is this Howard?
Howard: Of course not. It- It's Shatner. If you don't believe me, ask my good friend, Christopher Walken. [imitating Walken] Hello, Bill and I are just hanging out at The Polo Lounge.
Raj: Mr. Shatner, Mr. Walken, here are your martinis. [glass dings]
Howard: [whispering in normal voice] What are you doing?
Raj: I'm filling out the world.
Howard: You're ruining it.
Wil Wheaton: No, he's not.
Raj: Thanks, Wil.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Wil Wheaton: All right, Professor Proton fans, get ready to meet Dr. Sheldon Cooper and Dr. Amy Farrah Fowler, a pair of real-life scientists who may win the Nobel Prize. That's like the Kids' Choice Award, but with more science and less slime.

Sheldon: Kids' Choice Award? Why would they let kids choose anything? They're basically human larvae.
Wil Wheaton: Well, they are kind of our target audience.
Sheldon: Greetings, children. Toys, am I right?
Amy: He is. He has hundreds of them.

Wil Wheaton: So you two have discovered something that a lot of people are really excited about.
Amy: We have.
Wil Wheaton: Now, before you explain it, keep in mind that our average viewer is this many.