Leonard: Just give them a chance. Uh, science has a history of difficult people. Look at, uh, Newton, who was a jerk to Leibniz, and Leibniz, who was a jerk to everyone.
Penny: Yeah, you know, and I don't need to tell you that gravitational waves are disturbances in the curvature of space-time. Or that the- Hey, you worked on the movie Interstellar?

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

President Siebert: Look, it doesn't matter if they have popular support, we're gonna get the scientific community behind us.
Leonard: He's right, the Nobel Prize is about the work, and as your fellow scientists, we support you and Amy.
President Siebert: That's great, Scooby Gang.

President Siebert: Dr. Cooper, there you are. I just wanted to tell you not to worry about this Pemberton and Campbell publicity blitz.
Sheldon: Are you worried?
President Siebert: Not at all. Not even a little bit. [manic laugh]

Sheldon: Look at this. They posted another video. It's not even about science. They're on a celebrity bus tour.
Raj: Those are fun. I went on one and saw Tom Hanks talking to his gardener. He's even nice when you plant the wrong color azaleas.