Wolowitz: He doesn't do anything for me. If I were going to go that way, I'm more of a Zac Efron kind of guy.
Raj: Oh yeah, like you have a shot with Zac Efron.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Josh: So, I have to ask, was the robot sexy?
Howard: It was actually just a mechanical hand.
Josh: 'Cause that's all you need, right?
Howard: You are my brother.

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Sheldon: All I need is a healthy ovum and I can grow my own Leonard Nimoy.
Penny: Okay, all I'm giving you is the napkin, Sheldon.

Penny: Now, honey, it's okay. You don't have to get me anything in return.
Sheldon: Of course I do. The essence of the custom is that I now have to go out and purchase for you a gift of commensurate value and representing the same perceived level of friendship as that represented by the gift you've given me. It's no wonder suicide rates skyrocket this time of year.
Penny: Okay, you know what? Forget it. I'm not giving you a present.
Sheldon: No, it's too late. I see it. That elf sticker says to Sheldon. The die has been cast, the moving finger has writ, Hannibal has crossed the Alps.

Sheldon: If I would give you this gift basket, based on that action alone and no other data, infer and describe the hypothetical relationship that exist between us.
Store Clerk: Excuse me?
Sheldon: Here. Now, are we friends? Colleagues? Lovers? Are you my grandmother?
Store Clerk: I don't understand what you're talking about and you're making me a little uncomfortable.
Howard: See? Sounds just like you and Penny. We'll take it.