Sheldon: The thing about tomatoes, I think you will really enjoy this, is that they are shelved with the vegetables but they are technically a fruit.
Penny: Interesting.
Sheldon: Isn't it!
Penny: No, I mean what you find enjoyable.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Mary: He gets his temper from his daddy.
Leonard: Ah!
Mary: He's got my eyes.
Leonard: I see!
Mary: All that science stuff, that comes from Jesus.

Mary Cooper: I'm sorry, did I start that sentence with the words, "If it pleases your highness?"

Mary Cooper: You don't hunt, do you?