Sheldon: What did the toaster oven ever do to you?
Leonard: What did I do to Jimmy Mullins in the third grade? He still punched me in the face with my own fists. Sorry, you little nerd. You were just in the wrong boys' room at the wrong time.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Barry Kripke: We're all pathetic and creepy, and can't get girls. That's why we fight robots.

Mrs. Wolowitz: Want me to get you a popsicle?
Howard: Cherry, please!
Mrs. Wolowitz: I ate the cherry. All that's left is green.
Howard: You make me wanna kill myself!

Mrs. Wolowitz Howard, there's a blonde girl, Patsy, here to see you.
Howard: Who?
Mrs. Wolowitz Okay, now she's saying it's Penny.