Raj: Well, I've always had this fantasy that involves dancing. The sexual chemistry between my partner and me. But boy oh boy, does my father not approve until he sees us in the big dance competition.
Penny: Okay, that's just the plot for "Dirty Dancing".

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Sheldon: Sheldon Cooper does not get lucky.
Amy: You and me both, brother.

Sheldon: I've got to find a way to stop this thing.
Leonard: Buddy, I don't think you can. Once it's out there, it's out there. This thing is like the science equivalent of a sex tape.
Sheldon: Frankly, I'd prefer a sex tape.
Leonard: You don't know what a sex tape is, do you?
Sheldon: No.

Bernadette: Great news. A raccoon virus just crossed the species barrier and can now infect humans.
Raj: Why is that great news?
Bernadette: In the pharmaceutical business we have a saying: mo' infections, mo' money.