Leonard: Ladies do love a guy dressed like a kitchen garbage bag.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Leonard: [to a "smiling" Sheldon] We're here to see Koothrappali, not kill Batman.

Raj: Amy, good luck getting these guys excited about a dinner with a theme. I gave up when no one cared about my Tom Hanks-Giving.

Sheldon: Let's see. What do I know about Amy? She loves medieval literature. Chaucer's her favorite. And her eyes sparkle when she watches old French movies. And I enjoy how harp music causes her fingers to dance as if she's playing along.
Bernadette: Wow, you really do love her.
Sheldon: I do. Now, let's find the kind of gift that makes her feel small and worthless.

Bernadette: Why'd you turn it off?
Sheldon: Because in the last ten minutes, Santa came to town, kissed mommy, and ran grandma over with a reindeer. I had a drunk uncle who did all those things. Nobody sings songs about him.