Howard: I'm telling you, something is wrong. I can always feel it when Raj is in trouble.
Bernadette: Geez, how close were you guys before we got married?
Leonard: Don't look under that rock.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Sheldon: She's remarkable.
Leonard: She really is.
Sheldon: How is it that she can remember all those lines, yet as a waitress she can't remember no tomato on my hamburger?

Bernadette: It smells pretty ripe in here. You kinda feel it in your eyes.

Lucy: I'm kind of broken.
Raj: That's great. I'm broken, too.
Lucy: Oh, no you're not.
Raj: Oh, I totally am. If it wasn't for this beer, I couldn't even talk to you right now. I'm a wreck. There are many things seriously wrong with me. And not quirks, either. Like diagnosable psychological problems. Maybe brain damage.
Lucy: Well how do I know you're not just saying that?
Raj: Go out with me on one date. I promise you, you'll see.