Howard: Ow. Damn, paper cut. Nothing worse than a paper cut.
Raj: Well, obviously you don't remember your circumcision.

Raj: Oh man, first monster I see I'm gonna sneak up behind him, whip out my wand and shoot my magic all over his ass!
Stuart: Do you hear yourself when you say these things?

Raj: Amy, good luck getting these guys excited about a dinner with a theme. I gave up when no one cared about my Tom Hanks-Giving.

Penny: What do you mean new roommate? What happened to Leonard?
Sheldon: The same thing that happened to Homo Erectus. He was replaced by a superior species.
Raj: I'm the new homo in town.

Sheldon: Good Morning your honor, Dr. Sheldon Cooper appearing in pro se - that is to say representing himself.
Judge: I know what it means, I went to law school.
Sheldon: Yet you wound up in traffic court.

Sheldon: *After just being jailed, at the biggest guy in the cell who's sitting on a bench* That's my spot.

Sheldon: I would point out that I am at the top of my profession, while you preside over the kiddie table of yours.