Sheldon: Now, Penny, we don't consume alcohol during Dungeons and Dragons. It impairs our judgment.
Penny: Oh, this isn't alcohol. It's a magic potion that makes me like you.
Leonard: Double potion, please.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Sheldon: I've never played Dungeons and Dragons with girls.
Penny: It's okay, honey, no one has.

Howard: A satanic fungus that looks suspiciously like Al Pacino rises from the forest floor and says, (Imitating Al Pacino) "You're playing D&D. You're playing D&D. This whole apartment is playing D&D."

Amy: Go away. Sheldon is nibbling on my ... fourteen! Yes!