Howard: A satanic fungus that looks suspiciously like Al Pacino rises from the forest floor and says, (Imitating Al Pacino) "You're playing D&D. You're playing D&D. This whole apartment is playing D&D."

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Sheldon: I've never played Dungeons and Dragons with girls.
Penny: It's okay, honey, no one has.

Sheldon: Now, Penny, we don't consume alcohol during Dungeons and Dragons. It impairs our judgment.
Penny: Oh, this isn't alcohol. It's a magic potion that makes me like you.
Leonard: Double potion, please.

Amy: Go away. Sheldon is nibbling on my ... fourteen! Yes!