Penny: Oh and FYI, you never even heard of The Black Eyed Peas until you met me.
Leonard: I'd heard of them. Didn't know they were a band.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Sheldon: Stop it both of you! All this fighting, I might as well be back with my parents!
*Imitating his Mom* Dammit, George! I told you if you didn't quit drinking I would leave you!
*Imitating his Dad* Well, I guess that makes you a liar, because I'm drunk as hell and you are still here!
*Imitating his Mom* Stop yelling, you're making Sheldon cry!
*Imitating his Dad* I'll tell you what is making Sheldon cry, that I let you name him SHELDON!

Sheldon: You can't make a half sandwich. If it's not half of a whole sandwich, it's just a small sandwich.

Sheldon: Leonard, when that woman moved in three years ago I told you not to talk to her, and now look. We're going to be late for the movies.