Leonard: *to Wil Wheaton* Give me back that juice.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Leonard: [to a "smiling" Sheldon] We're here to see Koothrappali, not kill Batman.

Sheldon: It reminds me of when my stupid brother and sister would build forts in the living room, and wouldn't let me in. I hated that so much.
Amy: You know, there's nothing I can do about getting you invited to the symposium, but if you wanted we could build a fort.
Sheldon: Isn't that a little juvenile?
Amy: More juvenile than this? *Puts up picture of smiling Sheldon to her face*

Howard: Hey, I threw out the first pitch at an Angels game.
Josh: Wow.
Bernadette: He did it with a robot.
Josh: You had sex with a robot?
Howard: That's not what she meant.
Raj: But technically, yes.

Leonard: Hang on, if you're making all this money, where is it?
Penny: In a safe place.
Leonard: What does that mean, under your bed?
Penny: No, it means a diversified portfolio of stocks and bonds. I'm not overly conservative. I'm young, so my guy said I can afford to take some risks.
Leonard: Wait a minute, you have "a guy"?
Penny: Don't you have a guy?
Leonard: Why would I have a guy?! I don't have any money!