Bernadette: What's going on in here?
Howard: I am making molecular cocktails. This sphere is actually a cosmopolitan.
Bernadette: Oh. How do you drink it?
Howard: Just put it in your mouth and pop it like a zit.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Sheldon: *singing in the tune of "Bingo Was His Name-o"* There was a scientist who had a theory, and James Clerk Maxwell was his name-o. J-A-M-E-S, C-L-E-R-K, space, M-A-X-W-E-L-L, and James Clerk Maxwell was his name-o. There was a scientist who had a theory, and James Clerk Maxwell was his name-o. *claps* A-M-E-S--
Leonard: Okay, okay, we get it.

Howard: First take a picture with me.
Bernadette: Why?
Howard: Well, Raj and I always talked about learning how to make cocktails like this together, so I taught myself and I'm putting this on Instagram so he can see it and feel like a turd. Say cheese!

Sheldon: *singing in the tune of "Eye of the Tiger"* It's the eye of the tiger, it's the ear of the bat. It's the whiskers of a catfish and the walrus--
Howard: Hang on. Not that your song isn't terrible-- it is... but how do you mention bats and leave out sonar?
Sheldon: You didn't let me finish. *singing* And also regarding the bat. It has sonar.