Raj: Hello Mummy, Daddy, how are you?
Mrs. Koothrappali: Pretty good, can't complain.
Dr. Koothrappali: Oh I'm sure you can. Just give it a minute.

Penny: So, Dr. Koothrappali, long flight?
Dr. Koothrappali: Twenty hours.
Penny: Ooh, that's rough.
Dr. Koothrappali: Not at all. Did you know that when you fly Transcontinental without your wife, you don't pray for the plane to crash?

Dr. Koothrappali: Relax? Easy for you to say. Your mother isn't cleaning out your bank account. Forty years, the woman never cleaned a thing.

Bernadette: But I thought I'd be more excited.
Dr. Koothrappali: Oh, being excited isn't a guarantee of anything. Rajesh's mother was thrilled when she was pregnant with him. After he was born, she doted on his every move. And you know what happened? He broke her heart, moved halfway around the world, and dates only poor white women. So you never know.

Leonard: Once you open the box it loses its value.
Penny: Yeah, yeah. My mom gave me the same lecture about my virginity. I gotta tell you, it was a lot more fun taking it out and playing with it.

Leonard: You went to the comic book store by yourself?
Penny: Yeah, it was fun. I walked in and two different guys got asthma attacks. It felt pretty good.

Sheldon: I thought where you come from they don't have emotions.
Spock Doll: I come from a factory in Taiwan.