Bernadette: Everyone's a better mom than me.
Raj: Oh, don't take it so personally, maybe your baby's just a jerk.

Raj: Oh man, first monster I see I'm gonna sneak up behind him, whip out my wand and shoot my magic all over his ass!
Stuart: Do you hear yourself when you say these things?

Raj: Amy, good luck getting these guys excited about a dinner with a theme. I gave up when no one cared about my Tom Hanks-Giving.

Penny: What do you mean new roommate? What happened to Leonard?
Sheldon: The same thing that happened to Homo Erectus. He was replaced by a superior species.
Raj: I'm the new homo in town.

Amy: Well, uh, Howard and Bernadette had their baby.
Mary Cooper: (gasps) Oh, that's wonderful! Now, have they decided to raise it Jewish or regular?
Sheldon: Welcome to Texas.

Mary Cooper: Sheldon, if you're trying to prove me wrong, the tighty-whities on your head ain't changing my mind.

Sheldon: I knew we should've never mentioned us living together in the first place.
Amy: She was gonna find out eventually.
Sheldon: Disagree. We've known about evolution since 1859. She still believes in Noah and his amazing zoo boat.